Poult. Sci.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Morris, B.
Right arrow Articles by McElroy, A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Morris, B.
Right arrow Articles by McElroy, A.
Poultry Science, Vol 83, Issue 10, 1667-1674
Copyright © 2004 by Poultry Science Association

Articles

Intestinal mucosal mast cell immune response and pathogenesis of two Eimeria acervulina isolates in broiler chickens

BC Morris, HD Danforth, DJ Caldwell, FW Pierson, and AP McElroy

Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061-0306, USA.

Four experiments were conducted comparing intestinal immune responses to 2 isolates of Eimeria acervulina (EA), EA1 and EA2. In experiments 1 and 2, broiler chicks of 2 commercial breeds were divided into control (nonchallenged), EA1-, or EA2-challenged groups. On d 6 postchallenge (PC), changes in BW were determined, intestinal lesions were scored, and duodenal tissue was evaluated for morphometric alterations and mucosal mast cell numbers. EA1 produced classical duodenal lesions and reduced villus height to crypt depth ratios compared with controls; however, no differences were found in mast cell counts. EA2 produced different results, and observed data were suggestive of an anaphylactic-like intestinal secretory response compared with EA1 or controls. In experiment 3, tissues were analyzed from d 2 through 6 PC. Villus atrophy and crypt hyperplasia were increased on d 5 PC in both challenged groups. Mast cell counts were significantly greater on d 3 and 4 PC in EA1-challenged birds. In experiment 4, EA2 oocysts were cleaned with 5.25% sodium hypochlorite to evaluate the possibility of a bacterial contaminant contributing to the pathogenesis of intestinal alterations. No evidence of a bacterial contaminant contributing to the pathology was observed. These data are indicative of differential host response and immunovariability between different isolates of the same Eimeria species in 2 breeds of commercial broiler chickens.


This article has been cited by other articles:


Home page
 Poult. Sci.Home page
D. Wang, W. Ma, R. She, Qu. Sun, Y. Liu, Y. Hu, L. Liu, Y. Yang, and K. Peng
Effects of swine gut antimicrobial peptides on the intestinal mucosal immunity in specific-pathogen-free chickens
Poult. Sci., May 1, 2009; 88(5): 967 - 974.
[Abstract] [Full Text] [PDF]

Home page
 Poult. Sci.Home page
Q. Sun, W. Li, R. She, D. Wang, D. Han, R. Li, Y. Ding, and Z. Yue
Evidence for a role of mast cells in the mucosal injury induced by Newcastle disease virus
Poult. Sci., March 1, 2009; 88(3): 554 - 561.
[Abstract] [Full Text] [PDF]

Home page
 Poult. Sci.Home page
C. B. Collins, J. McGrath, A. W. Baird, and D. P. Campion
Effect of Mast Cell Degranulation on Chicken Ileal Ion Transport In Vitro
Poult. Sci., May 1, 2007; 86(5): 843 - 849.
[Abstract] [Full Text] [PDF]

Home page
 Poult. Sci.Home page
M. E. Hume, S. Clemente-Hernandez, and E. O. Oviedo-Rondon
Effects of Feed Additives and Mixed Eimeria Species Infection on Intestinal Microbial Ecology of Broilers
Poult. Sci., December 1, 2006; 85(12): 2106 - 2111.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2004 by the Poultry Science Association.