HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via ISI Web of Science (8) Citing Articles via Google Scholar Google Scholar Articles by Siegel, P. B. Articles by Andersson, L. Search for Related Content PubMed PubMed Citation Articles by Siegel, P. B. Articles by Andersson, L.

Progress from Chicken Genetics to the Chicken Genome

P. B. Siegel^*,1, J. B. Dodgson and L. Andersson^,

^* Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg 24061; Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing 48824; Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23, Sweden; and Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, BMC, SE-75 124, Uppsala, Sweden

¹ Corresponding author: pbsiegel{at}vt.edu

The chicken has a proud history, both in genetic research and as a source of food. Here we attempt to provide an overview of past contributions of the chicken in both arenas and to link those contributions to the near future from a genetic perspective. Companion articles will discuss current poultry genetics research in greater detail. The chicken was the first animal species in which Mendelian inheritance was demonstrated. A century later, the chicken was the first among farm animals to have its genome sequenced. Between these firsts, the chicken remained a key organism used in genetic research. Breeding programs, based on sound genetic principles, facilitated the global emergence of the chicken meat and egg industries. Concomitantly, the chicken served as a model whose experimental populations and mutant stocks were used in basic and applied studies with broad application to other species, including humans. In this paper, we review some of these contributions, trace the path from the origin of molecular genetics to the sequence of the chicken genome, and discuss the merits of the chicken as a model organism for furthering our understanding of biology.

Key Words: domestication • animal model • genome sequence • genome mapping • quantitative trait loci

This article has been cited by other articles:

				S. Druyan, J. E. de Oliveira, and C. M. Ashwell Focused Microarrays as a Method to Evaluate Subtle Changes in Gene Expression Poult. Sci., November 1, 2008; 87(11): 2418 - 2429. [Abstract] [Full Text] [PDF]

				C. G. Scanes Flowering of Science Poult. Sci., March 1, 2008; 87(3): 397 - 398. [Full Text] [PDF]

				L. A. Cogburn, T. E. Porter, M. J. Duclos, J. Simon, S. C. Burgess, J. J. Zhu, H. H. Cheng, J. B. Dodgson, and J. Burnside Functional Genomics of the Chicken A Model Organism Poult. Sci., October 1, 2007; 86(10): 2059 - 2094. [Abstract] [Full Text] [PDF]

				J. B. Dodgson The Chicken Genome: Some Good News and Some Bad News Poult. Sci., July 1, 2007; 86(7): 1453 - 1459. [Abstract] [Full Text] [PDF]

				S. J. Lamont Perspectives in Chicken Genetics and Genomics Poult. Sci., December 1, 2006; 85(12): 2048 - 2049. [Abstract] [Full Text] [PDF]